Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/19508
Title: TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling.
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Issue Date: Jul-2015
Citation: Mol Cell Oncol.;(2)3:e980134
Abstract: In a recent article, we found that Tribbles pseudokinase 3 (TRIB3) plays a tumor suppressor role and that this effect relies on the dysregulation of the phosphorylation of v-akt murine thymoma viral oncogene homolog (AKT) by the mammalian target of rapamycin complex 2 (mTORC2 complex), and the subsequent hyperphosphorylation and inactivation of the transcription factor Forkhead box O3 (FOXO3).
PMID: 27308456
URI: https://hdl.handle.net/20.500.12530/19508
Rights: openAccess
ISSN: 2372-3556
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. 12 de Octubre > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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