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Title: Curcumin Mitigates the Intracellular Lipid Deposit Induced by Antipsychotics In Vitro.
Issue Date: 2015
Citation: PLoS ONE.2015;(10)10:e0141829
Abstract: First- and second-generation antipsychotics (FGAs and SGAs, respectively), both inhibit cholesterol biosynthesis and impair the intracellular cholesterol trafficking, leading to lipid accumulation in the late endosome/lysosome compartment. In this study we examined if curcumin, a plant polyphenol that stimulates exosome release, can alleviate antipsychotic-induced intracellular lipid accumulation.
PMID: 26517556
Rights: openAccess
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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