Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/20600
Title: Proteins of Bartonella bacilliformis: Candidates for Vaccine Development.
Authors: 
Issue Date: 2015
Citation: Int J Pept.2015;(2015):702784
Abstract: Bartonella bacilliformis is the etiologic agent of Carrión's disease or Oroya fever. B. bacilliformis infection represents an interesting model of human host specificity. The notable differences in clinical presentations of Carrión's disease suggest complex adaptations by the bacterium to the human host, with the overall objectives of persistence, maintenance of a reservoir state for vectorial transmission, and immune evasion. These events include a multitude of biochemical and genetic mechanisms involving both bacterial and host proteins. This review focuses on proteins involved in interactions between B. bacilliformis and the human host. Some of them (e.g., flagellin, Brps, IalB, FtsZ, Hbp/Pap31, and other outer membrane proteins) are potential protein antigen candidates for a synthetic vaccine.
PMID: 26413097
URI: https://hdl.handle.net/20.500.12530/20600
Rights: openAccess
ISSN: 1687-9767
Appears in Collections:Hospitales > H. U. Fundación Alcorcón > Artículos

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