Comparison between xenogeneic and allogeneic adipose mesenchymal stem cells in the treatment of acute cerebral infarct: proof of concept in rats.

Document types check

Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/22902

Title:	Comparison between xenogeneic and allogeneic adipose mesenchymal stem cells in the treatment of acute cerebral infarct: proof of concept in rats.
Authors:	Gutiérrez-Fernández, María Rodríguez-Frutos, Berta Ramos-Cejudo, Jaime Otero-Ortega, Laura Fuentes, Blanca Vallejo-Cremades, María Teresa Sanz-Cuesta, Borja Enrique Díez-Tejedor, Exuperio View more
Mesh:	Acute Disease Adipose Tissue Animals Biomarkers Cell Death Cerebral Infarction Humans Infarction, Middle Cerebral Artery Male Mesenchymal Stem Cells Rats, Sprague-Dawley Tissue Distribution Transplantation, Homologous Mesenchymal Stem Cell Transplantation Transplantation, Heterologous View more
Issue Date:	1-Feb-2015
Citation:	J Transl Med.2015 Feb;(13):46
Abstract:	Rat adipose tissue-derived-mesenchymal stem cells (rAD-MSCs) have proven to be safe in experimental animal models of stroke. However, in order to use human AD-MSCs (hAD-MSCs) as a treatment for stroke patients, a proof of concept is needed. We analyzed whether the xenogeneic hAD-MSCs were as safe and effective as allogeneic rAD-MSCs in permanent Middle Cerebral Artery Occlusion (pMCAO) in rats.
PMID:	25637958
URI:	https://hdl.handle.net/20.500.12530/22902
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos Hospitales > H. U. La Paz > Artículos

Files in This Item:

File	Description	Size	Format
PMC4322805.pdf		3.21 MB	Adobe PDF	View/Open