Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial.

Brunner, Hermine I; Ruperto, Nicolino; Zuber, Zbigniew; Keane, Caroline; Harari, Olivier; Kenwright, Andrew; Lu, Peng; Cuttica, Ruben; Keltsev, Vladimir; Xavier, Ricardo M; Calvo, Inmaculada; Nikishina, Irina; Rubio-Pérez, Nadina; Alexeeva, Ekaterina; Chasnyk, Vyacheslav; Horneff, Gerd; Opoka-Winiarska, Violetta; Quartier, Pierre; Silva, Clovis A; Silverman, Earl; Spindler, Alberto; Baildam, Eileen; Gámir, M Luz; Martin, Alan; Rietschel, Christoph; Siri, Daniel; Smolewska, Elzbieta; Lovell, Daniel; Martini, Alberto; De Benedetti, Fabrizio

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/23760

Title:	Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial.
Authors:	Brunner, Hermine I Ruperto, Nicolino Zuber, Zbigniew Keane, Caroline Harari, Olivier Kenwright, Andrew Lu, Peng Cuttica, Ruben Keltsev, Vladimir Xavier, Ricardo M Calvo, Inmaculada Nikishina, Irina Rubio-Pérez, Nadina Alexeeva, Ekaterina Chasnyk, Vyacheslav Horneff, Gerd Opoka-Winiarska, Violetta Quartier, Pierre Silva, Clovis A Silverman, Earl Spindler, Alberto Baildam, Eileen Gámir, M Luz Martin, Alan Rietschel, Christoph Siri, Daniel Smolewska, Elzbieta Lovell, Daniel Martini, Alberto De Benedetti, Fabrizio View more
Keywords:	DMARDs (biologic) Juvenile Idiopathic Arthritis Treatment View more
Mesh:	Adolescent Adrenal Cortex Hormones Antibodies, Monoclonal, Humanized Antirheumatic Agents Arthritis, Juvenile Bronchitis Cellulitis Child Child, Preschool Disease Progression Double-Blind Method Drug Therapy, Combination Female Humans Maintenance Chemotherapy Male Methotrexate Pneumonia Receptors, Interleukin-6 Remission Induction Treatment Outcome View more
Issue Date:	Jun-2015
Citation:	Ann. Rheum. Dis..2015 Jun;(74)6:1110-7
Abstract:	To evaluate the interleukin-6 receptor inhibitor tocilizumab for the treatment of patients with polyarticular-course juvenile idiopathic arthritis (pcJIA).
PMID:	24834925
URI:	https://hdl.handle.net/20.500.12530/23760
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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