Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/24232
Title: Melatonin and Nitrones As Potential Therapeutic Agents for Stroke.
Authors: 
Keywords: 
Issue Date: 2016
Citation: Front Aging Neurosci.2016;(8):281
Abstract: Stroke is a disease of aging affecting millions of people worldwide, and recombinant tissue-type plasminogen activator (r-tPA) is the only treatment approved. However, r-tPA has a low therapeutic window and secondary effects which limit its beneficial outcome, urging thus the search for new more efficient therapies. Among them, neuroprotection based on melatonin or nitrones, as free radical traps, have arisen as drug candidates due to their strong antioxidant power. In this Perspective article, an update on the specific results of the melatonin and several new nitrones are presented.
PMID: 27932976
URI: https://hdl.handle.net/20.500.12530/24232
Rights: openAccess
ISSN: 1663-4365
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos
Hospitales > H. U. La Paz > Artículos

Files in This Item:
File Description SizeFormat 
PMC5120103.pdf903.32 kBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.