IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C.

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/25381

Title:	IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C.
Authors:	Krämer, Benjamin Finnemann, Claudia Sastre, Beatriz Lutz, Philipp Glässner, Andreas Wolter, Franziska Goeser, Felix Kokordelis, Pavlos Kaczmarek, Dominik Nischalke, Hans-Dieter Strassburg, Christian P Spengler, Ulrich Nattermann, Jacob View more
Mesh:	Female Genotype Hepatitis C Humans Interleukin-12 Interleukins Killer Cells, Natural Lymphocyte Activation Male Middle Aged Monocytes Genetic Variation View more
Issue Date:	2016
Citation:	PLoS ONE.2016;(11)9:e0162068
Abstract:	Immuno-genetic studies suggest a functional link between NK cells and λ-IFNs. We recently showed that NK cells are negative for the IFN-λ receptor IFN-λR1 and do not respond to IFN-λ, suggesting a rather indirect association between IL-28B genotype and NK cell activity.
PMID:	27583440
URI:	https://hdl.handle.net/20.500.12530/25381
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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