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|Title:||Thr105Ile (rs11558538) polymorphism in the histamine N-methyltransferase (HNMT) gene and risk for Parkinson disease: A PRISMA-compliant systematic review and meta-analysis.|
|Citation:||Medicine (Baltimore).2016 Jul;(95)27:e4147|
|Abstract:||Several neuropathological, biochemical, and pharmacological data suggested a possible role of histamine in the etiopathogenesis of Parkinson disease (PD). The single nucleotide polymorphism (SNP) rs11558538 in the histamine N-methyltransferase (HNMT) gene has been associated with the risk of developing PD by several studies but not by some others. We carried out a systematic review that included all the studies published on PD risk related to the rs11558538 SNP, and we conducted a meta-analysis following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.|
|Appears in Collections:||Hospitales > H. U. Sureste > Artículos|
Fundaciones e Institutos de Investigación > FIB H. U. Príncipe de Asturias > Artículos
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