Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/26661
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dc.contributor.authorQuintero, Enrique
dc.contributor.authorCarrillo, Marta
dc.contributor.authorLeoz, Maria-Liz
dc.contributor.authorCubiella, Joaquin
dc.contributor.authorGargallo, Carla
dc.contributor.authorLanas, Angel
dc.contributor.authorBujanda, Luis
dc.contributor.authorGimeno-García, Antonio Z
dc.contributor.authorHernández-Guerra, Manuel
dc.contributor.authorNicolás-Pérez, David
dc.contributor.authorAlonso-Abreu, Inmaculada
dc.contributor.authorMorillas, Juan Diego
dc.contributor.authorBalaguer, Francesc
dc.contributor.authorMuriel, Alfonso
dc.date.accessioned2019-06-28T15:00:59Z-
dc.date.available2019-06-28T15:00:59Z-
dc.date.issued2016-05
dc.identifier.citationPLoS Med..2016 May;(13)5:e1002008
dc.identifier.urihttps://hdl.handle.net/20.500.12530/26661-
dc.description.abstractFirst-degree relatives (FDR) of patients with colorectal cancer have a higher risk of developing colorectal cancer than the general population. For this reason, screening guidelines recommend colonoscopy every 5 or 10 y, starting at the age of 40, depending on whether colorectal cancer in the index-case is diagnosed at <60 or ≥60 y, respectively. However, studies on the risk of neoplastic lesions are inconclusive. The aim of this study was to determine the risk of advanced neoplasia (three or more non-advanced adenomas, advanced adenoma, or invasive cancer) in FDR of patients with colorectal cancer compared to average-risk individuals (i.e., asymptomatic adults 50 to 69 y of age with no family history of colorectal cancer).
dc.language.isoeng
dc.rightsopenAccess-
dc.subject.meshAdenoma
dc.subject.meshAdult
dc.subject.meshAge Factors
dc.subject.meshAged
dc.subject.meshColonoscopy
dc.subject.meshColorectal Neoplasms
dc.subject.meshCross-Sectional Studies
dc.subject.meshEarly Detection of Cancer
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshRisk Factors
dc.subject.meshSex Factors
dc.subject.meshSpain
dc.subject.meshFamily
dc.titleRisk of Advanced Neoplasia in First-Degree Relatives with Colorectal Cancer: A Large Multicenter Cross-Sectional Study.
dc.typeArtículo
dc.identifier.pubmedID27138769
dc.format.volume13
dc.format.pagee1002008
dc.identifier.e-issn1549-1676
dc.identifier.journalPLoS medicine
dc.identifier.doi10.1371/journal.pmed.1002008
dc.format.number5
dc.identifier.pmcPMC4854417
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
Appears in Collections:Hospitales > H. U. Clínico San Carlos > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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