Please use this identifier to cite or link to this item:
|Title:||Acquired multi-azole resistance in Candida tropicalis during persistent urinary tract infection in a dog.|
|Citation:||Med Mycol Case Rep.2016 Mar;(11):9-12|
|Abstract:||Multi-azole resistance acquisition by Candida tropicalis after prolonged antifungal therapy in a dog with urinary candidiasis is reported. Pre- and post-azole treatment isolates were clonally related and had identical silent mutations in the ERG11 gene, but the latter displayed increased azole minimum inhibitory concentrations. A novel frameshift mutation in ERG3 was found in some isolates recovered after resistance development, so it appears unlikely that this mutation is responsible for multi-azole resistance.|
|Appears in Collections:||Fundaciones e Institutos de Investigación > IIS H. General U. Gregorio Marañón > Artículos|
Files in This Item:
|PMC4760230.pdf||627.51 kB||Adobe PDF|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.