No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

Hollestelle, Antoinette; van der Baan, Frederieke H; Berchuck, Andrew; Johnatty, Sharon E; Aben, Katja K; Agnarsson, Bjarni A; Aittomäki, Kristiina; Alducci, Elisa; Andrulis, Irene L; Anton-Culver, Hoda; Antonenkova, Natalia N; Antoniou, Antonis C; Apicella, Carmel; Arndt, Volker; Arnold, Norbert; Arun, Banu K; Arver, Brita; Ashworth, Alan; Baglietto, Laura; Balleine, Rosemary; Bandera, Elisa V; Barrowdale, Daniel; Bean, Yukie T; Beckmann, Lars; Beckmann, Matthias W; Benitez, Javier; Berger, Andreas; Berger, Raanan; Beuselinck, Benoit; Bisogna, Maria; Bjorge, Line; Blomqvist, Carl; Bogdanova, Natalia V; Bojesen, Anders; Bojesen, Stig E; Bolla, Manjeet K; Bonanni, Bernardo; Brand, Judith S; Brauch, Hiltrud; Brenner, Hermann; Brinton, Louise; Brooks-Wilson, Angela; Bruinsma, Fiona; Brunet, Joan; Brüning, Thomas; Budzilowska, Agnieszka; Bunker, Clareann H; Burwinkel, Barbara; Butzow, Ralf; Buys, Saundra S; Caligo, Maria A; Campbell, Ian; Carter, Jonathan; Chang-Claude, Jenny; Chanock, Stephen J; Claes, Kathleen B M; Collée, J Margriet; Cook, Linda S; Couch, Fergus J; Cox, Angela; Cramer, Daniel; Cross, Simon S; Cunningham, Julie M; Cybulski, Cezary; Czene, Kamila; Damiola, Francesca; Dansonka-Mieszkowska, Agnieszka; Darabi, Hatef; de la Hoya, Miguel; deFazio, Anna; Dennis, Joseph; Devilee, Peter; Dicks, Ed M; Diez, Orland; Doherty, Jennifer A; Domchek, Susan M; Dorfling, Cecilia M; Dörk, Thilo; Silva, Isabel Dos Santos; du Bois, Andreas; Dumont, Martine; Dunning, Alison M; Duran, Mercedes; Easton, Douglas F; Eccles, Diana; Edwards, Robert P; Ehrencrona, Hans; Ejlertsen, Bent; Ekici, Arif B; Ellis, Steve D; Engel, Christoph; Eriksson, Mikael; Fasching, Peter A; Feliubadalo, Lidia; Figueroa, Jonine; Flesch-Janys, Dieter; Fletcher, Olivia; Fontaine, Annette; Fortuzzi, Stefano; Fostira, Florentia; Fridley, Brooke L; Friebel, Tara; Friedman, Eitan; Friel, Grace; Frost, Debra; Garber, Judy; García-Closas, Montserrat; Gayther, Simon A; Gentry-Maharaj, Aleksandra; Gerdes, Anne-Marie; Giles, Graham G; Glasspool, Rosalind; Glendon, Gord; Godwin, Andrew K; Goodman, Marc T; Gore, Martin; Greene, Mark H; Grip, Mervi; Gronwald, Jacek; Gschwantler Kaulich, Daphne; Guénel, Pascal; Guzman, Starr R; Haeberle, Lothar; Haiman, Christopher A; Hall, Per; Halverson, Sandra L; Hamann, Ute; Hansen, Thomas V O; Harter, Philipp; Hartikainen, Jaana M; Healey, Sue; Hein, Alexander; Heitz, Florian; Henderson, Brian E; Herzog, Josef; T Hildebrandt, Michelle A; Høgdall, Claus K; Høgdall, Estrid; Hogervorst, Frans B L; Hopper, John L; Humphreys, Keith; Huzarski, Tomasz; Imyanitov, Evgeny N; Isaacs, Claudine; Jakubowska, Anna; Janavicius, Ramunas; Jaworska, Katarzyna; Jensen, Allan; Jensen, Uffe Birk; Johnson, Nichola; Jukkola-Vuorinen, Arja; Kabisch, Maria; Karlan, Beth Y; Kataja, Vesa; Kauff, Noah; Kelemen, Linda E; Kerin, Michael J; Kiemeney, Lambertus A; Kjaer, Susanne K; Knight, Julia A; Knol-Bout, Jacoba P; Konstantopoulou, Irene; Kosma, Veli-Matti; Krakstad, Camilla; Kristensen, Vessela; Kuchenbaecker, Karoline B; Kupryjanczyk, Jolanta; Laitman, Yael; Lambrechts, Diether; Lambrechts, Sandrina; Larson, Melissa C; Lasa, Adriana; Laurent-Puig, Pierre; Lazaro, Conxi; Le, Nhu D; Le Marchand, Loic; Leminen, Arto; Lester, Jenny; Levine, Douglas A; Li, Jingmei; Liang, Dong; Lindblom, Annika; Lindor, Noralane; Lissowska, Jolanta; Long, Jirong; Lu, Karen H; Lubinski, Jan; Lundvall, Lene; Lurie, Galina; Mai, Phuong L; Mannermaa, Arto; Margolin, Sara; Mariette, Frederique; Marme, Frederik; Martens, John W M; Massuger, Leon F A G; Maugard, Christine; Mazoyer, Sylvie; McGuffog, Lesley; McGuire, Valerie; McLean, Catriona; McNeish, Iain; Meindl, Alfons; Menegaux, Florence; Menéndez, Primitiva; Menkiszak, Janusz; Menon, Usha; Mensenkamp, Arjen R; Miller, Nicola; Milne, Roger L; Modugno, Francesmary; Montagna, Marco; Moysich, Kirsten B; Müller, Heiko; Mulligan, Anna Marie; Muranen, Taru A; Narod, Steven A; Nathanson, Katherine L; Ness, Roberta B; Neuhausen, Susan L; Nevanlinna, Heli; Neven, Patrick; Nielsen, Finn C; Nielsen, Sune F; Nordestgaard, Børge G; Nussbaum, Robert L; Odunsi, Kunle; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I; Olson, Janet E; Olson, Sara H; Oosterwijk, Jan C; Orlow, Irene; Orr, Nick; Orsulic, Sandra; Osorio, Ana; Ottini, Laura; Paul, James; Pearce, Celeste L; Pedersen, Inge Sokilde; Peissel, Bernard; Pejovic, Tanja; Pelttari, Liisa M; Perkins, Jo; Permuth-Wey, Jenny; Peterlongo, Paolo; Peto, Julian; Phelan, Catherine M; Phillips, Kelly-Anne; Piedmonte, Marion; Pike, Malcolm C; Platte, Radka; Plisiecka-Halasa, Joanna; Poole, Elizabeth M; Poppe, Bruce; Pylkäs, Katri; Radice, Paolo; Ramus, Susan J; Rebbeck, Timothy R; Reed, Malcolm W R; Rennert, Gad; Risch, Harvey A; Robson, Mark; Rodriguez, Gustavo C; Romero, Atocha; Rossing, Mary Anne; Rothstein, Joseph H; Rudolph, Anja; Runnebaum, Ingo; Salani, Ritu; Salvesen, Helga B; Sawyer, Elinor J; Schildkraut, Joellen M; Schmidt, Marjanka K; Schmutzler, Rita K; Schneeweiss, Andreas; Schoemaker, Minouk J; Schrauder, Michael G; Schumacher, Fredrick; Schwaab, Ira; Scuvera, Giulietta; Sellers, Thomas A; Severi, Gianluca; Seynaeve, Caroline M; Shah, Mitul; Shrubsole, Martha; Siddiqui, Nadeem; Sieh, Weiva; Simard, Jacques; Singer, Christian F; Sinilnikova, Olga M; Smeets, Dominiek; Sohn, Christof; Soller, Maria; Song, Honglin; Soucy, Penny; Southey, Melissa C; Stegmaier, Christa; Stoppa-Lyonnet, Dominique; Sucheston, Lara; Swerdlow, Anthony; Tangen, Ingvild L; Tea, Muy-Kheng; Teixeira, Manuel R; Terry, Kathryn L; Terry, Mary Beth; Thomassen, Mads; Thompson, Pamela J; Tihomirova, Laima; Tischkowitz, Marc; Toland, Amanda Ewart; Tollenaar, Rob A E M; Tomlinson, Ian; Torres, Diana; Truong, Thérèse; Tsimiklis, Helen; Tung, Nadine; Tworoger, Shelley S; Tyrer, Jonathan P; Vachon, Celine M; Van 't Veer, Laura J; van Altena, Anne M; Van Asperen, C J; van den Berg, David; van den Ouweland, Ans M W; van Doorn, Helena C; Van Nieuwenhuysen, Els; van Rensburg, Elizabeth J; Vergote, Ignace; Verhoef, Senno; Vierkant, Robert A; Vijai, Joseph; Vitonis, Allison F; von Wachenfeldt, Anna; Walsh, Christine; Wang, Qin; Wang-Gohrke, Shan; Wappenschmidt, Barbara; Weischer, Maren; Weitzel, Jeffrey N; Weltens, Caroline; Wentzensen, Nicolas; Whittemore, Alice S; Wilkens, Lynne R; Winqvist, Robert; Wu, Anna H; Wu, Xifeng; Yang, Hannah P; Zaffaroni, Daniela; Pilar Zamora, M; Zheng, Wei; Ziogas, Argyrios; Chenevix-Trench, Georgia; Pharoah, Paul D P; Rookus, Matti A; Hooning, Maartje J; Goode, Ellen L

Document types check

Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/28922

Title:	No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Authors:	Hollestelle, Antoinette van der Baan, Frederieke H Berchuck, Andrew Johnatty, Sharon E Aben, Katja K Agnarsson, Bjarni A Aittomäki, Kristiina Alducci, Elisa Andrulis, Irene L Anton-Culver, Hoda Antonenkova, Natalia N Antoniou, Antonis C Apicella, Carmel Arndt, Volker Arnold, Norbert Arun, Banu K Arver, Brita Ashworth, Alan Baglietto, Laura Balleine, Rosemary Bandera, Elisa V Barrowdale, Daniel Bean, Yukie T Beckmann, Lars Beckmann, Matthias W Benitez, Javier Berger, Andreas Berger, Raanan Beuselinck, Benoit Bisogna, Maria Bjorge, Line Blomqvist, Carl Bogdanova, Natalia V Bojesen, Anders Bojesen, Stig E Bolla, Manjeet K Bonanni, Bernardo Brand, Judith S Brauch, Hiltrud Brenner, Hermann Brinton, Louise Brooks-Wilson, Angela Bruinsma, Fiona Brunet, Joan Brüning, Thomas Budzilowska, Agnieszka Bunker, Clareann H Burwinkel, Barbara Butzow, Ralf Buys, Saundra S Caligo, Maria A Campbell, Ian Carter, Jonathan Chang-Claude, Jenny Chanock, Stephen J Claes, Kathleen B M Collée, J Margriet Cook, Linda S Couch, Fergus J Cox, Angela Cramer, Daniel Cross, Simon S Cunningham, Julie M Cybulski, Cezary Czene, Kamila Damiola, Francesca Dansonka-Mieszkowska, Agnieszka Darabi, Hatef de la Hoya, Miguel deFazio, Anna Dennis, Joseph Devilee, Peter Dicks, Ed M Diez, Orland Doherty, Jennifer A Domchek, Susan M Dorfling, Cecilia M Dörk, Thilo Silva, Isabel Dos Santos du Bois, Andreas Dumont, Martine Dunning, Alison M Duran, Mercedes Easton, Douglas F Eccles, Diana Edwards, Robert P Ehrencrona, Hans Ejlertsen, Bent Ekici, Arif B Ellis, Steve D Engel, Christoph Eriksson, Mikael Fasching, Peter A Feliubadalo, Lidia Figueroa, Jonine Flesch-Janys, Dieter Fletcher, Olivia Fontaine, Annette Fortuzzi, Stefano Fostira, Florentia Fridley, Brooke L Friebel, Tara Friedman, Eitan Friel, Grace Frost, Debra Garber, Judy García-Closas, Montserrat Gayther, Simon A Gentry-Maharaj, Aleksandra Gerdes, Anne-Marie Giles, Graham G Glasspool, Rosalind Glendon, Gord Godwin, Andrew K Goodman, Marc T Gore, Martin Greene, Mark H Grip, Mervi Gronwald, Jacek Gschwantler Kaulich, Daphne Guénel, Pascal Guzman, Starr R Haeberle, Lothar Haiman, Christopher A Hall, Per Halverson, Sandra L Hamann, Ute Hansen, Thomas V O Harter, Philipp Hartikainen, Jaana M Healey, Sue Hein, Alexander Heitz, Florian Henderson, Brian E Herzog, Josef T Hildebrandt, Michelle A Høgdall, Claus K Høgdall, Estrid Hogervorst, Frans B L Hopper, John L Humphreys, Keith Huzarski, Tomasz Imyanitov, Evgeny N Isaacs, Claudine Jakubowska, Anna Janavicius, Ramunas Jaworska, Katarzyna Jensen, Allan Jensen, Uffe Birk Johnson, Nichola Jukkola-Vuorinen, Arja Kabisch, Maria Karlan, Beth Y Kataja, Vesa Kauff, Noah Kelemen, Linda E Kerin, Michael J Kiemeney, Lambertus A Kjaer, Susanne K Knight, Julia A Knol-Bout, Jacoba P Konstantopoulou, Irene Kosma, Veli-Matti Krakstad, Camilla Kristensen, Vessela Kuchenbaecker, Karoline B Kupryjanczyk, Jolanta Laitman, Yael Lambrechts, Diether Lambrechts, Sandrina Larson, Melissa C Lasa, Adriana Laurent-Puig, Pierre Lazaro, Conxi Le, Nhu D Le Marchand, Loic Leminen, Arto Lester, Jenny Levine, Douglas A Li, Jingmei Liang, Dong Lindblom, Annika Lindor, Noralane Lissowska, Jolanta Long, Jirong Lu, Karen H Lubinski, Jan Lundvall, Lene Lurie, Galina Mai, Phuong L Mannermaa, Arto Margolin, Sara Mariette, Frederique Marme, Frederik Martens, John W M Massuger, Leon F A G Maugard, Christine Mazoyer, Sylvie McGuffog, Lesley McGuire, Valerie McLean, Catriona McNeish, Iain Meindl, Alfons Menegaux, Florence Menéndez, Primitiva Menkiszak, Janusz Menon, Usha Mensenkamp, Arjen R Miller, Nicola Milne, Roger L Modugno, Francesmary Montagna, Marco Moysich, Kirsten B Müller, Heiko Mulligan, Anna Marie Muranen, Taru A Narod, Steven A Nathanson, Katherine L Ness, Roberta B Neuhausen, Susan L Nevanlinna, Heli Neven, Patrick Nielsen, Finn C Nielsen, Sune F Nordestgaard, Børge G Nussbaum, Robert L Odunsi, Kunle Offit, Kenneth Olah, Edith Olopade, Olufunmilayo I Olson, Janet E Olson, Sara H Oosterwijk, Jan C Orlow, Irene Orr, Nick Orsulic, Sandra Osorio, Ana Ottini, Laura Paul, James Pearce, Celeste L Pedersen, Inge Sokilde Peissel, Bernard Pejovic, Tanja Pelttari, Liisa M Perkins, Jo Permuth-Wey, Jenny Peterlongo, Paolo Peto, Julian Phelan, Catherine M Phillips, Kelly-Anne Piedmonte, Marion Pike, Malcolm C Platte, Radka Plisiecka-Halasa, Joanna Poole, Elizabeth M Poppe, Bruce Pylkäs, Katri Radice, Paolo Ramus, Susan J Rebbeck, Timothy R Reed, Malcolm W R Rennert, Gad Risch, Harvey A Robson, Mark Rodriguez, Gustavo C Romero, Atocha Rossing, Mary Anne Rothstein, Joseph H Rudolph, Anja Runnebaum, Ingo Salani, Ritu Salvesen, Helga B Sawyer, Elinor J Schildkraut, Joellen M Schmidt, Marjanka K Schmutzler, Rita K Schneeweiss, Andreas Schoemaker, Minouk J Schrauder, Michael G Schumacher, Fredrick Schwaab, Ira Scuvera, Giulietta Sellers, Thomas A Severi, Gianluca Seynaeve, Caroline M Shah, Mitul Shrubsole, Martha Siddiqui, Nadeem Sieh, Weiva Simard, Jacques Singer, Christian F Sinilnikova, Olga M Smeets, Dominiek Sohn, Christof Soller, Maria Song, Honglin Soucy, Penny Southey, Melissa C Stegmaier, Christa Stoppa-Lyonnet, Dominique Sucheston, Lara Swerdlow, Anthony Tangen, Ingvild L Tea, Muy-Kheng Teixeira, Manuel R Terry, Kathryn L Terry, Mary Beth Thomassen, Mads Thompson, Pamela J Tihomirova, Laima Tischkowitz, Marc Toland, Amanda Ewart Tollenaar, Rob A E M Tomlinson, Ian Torres, Diana Truong, Thérèse Tsimiklis, Helen Tung, Nadine Tworoger, Shelley S Tyrer, Jonathan P Vachon, Celine M Van 't Veer, Laura J van Altena, Anne M Van Asperen, C J van den Berg, David van den Ouweland, Ans M W van Doorn, Helena C Van Nieuwenhuysen, Els van Rensburg, Elizabeth J Vergote, Ignace Verhoef, Senno Vierkant, Robert A Vijai, Joseph Vitonis, Allison F von Wachenfeldt, Anna Walsh, Christine Wang, Qin Wang-Gohrke, Shan Wappenschmidt, Barbara Weischer, Maren Weitzel, Jeffrey N Weltens, Caroline Wentzensen, Nicolas Whittemore, Alice S Wilkens, Lynne R Winqvist, Robert Wu, Anna H Wu, Xifeng Yang, Hannah P Zaffaroni, Daniela Pilar Zamora, M Zheng, Wei Ziogas, Argyrios Chenevix-Trench, Georgia Pharoah, Paul D P Rookus, Matti A Hooning, Maartje J Goode, Ellen L View more
Keywords:	Breast cancer Clinical outcome Genetic association KRAS variant Ovarian cancer View more
Mesh:	Breast Neoplasms Carcinoma, Ovarian Epithelial Female Humans Neoplasms, Glandular and Epithelial Ovarian Neoplasms Proto-Oncogene Proteins p21(ras) View more
Issue Date:	2016
Citation:	Gynecol. Oncol..2016 05;(141)2:386-401
Abstract:	Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3' UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with survival time. However, prior studies, emphasizing particular subgroups, were relatively small. Therefore, we comprehensively evaluated ovarian and breast cancer risks as well as clinical outcome associated with rs61764370.
PMID:	25940428
URI:	https://hdl.handle.net/20.500.12530/28922
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos Hospitales > H. U. La Paz > Artículos

Files in This Item:

File	Description	Size	Format
PMC4630206.pdf		713.96 kB	Adobe PDF	View/Open

Show full item record