Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/30080
Title: HIF pathway and c-Myc as biomarkers for response to sunitinib in metastatic clear-cell renal cell carcinoma.
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Issue Date: 2017
Citation: Onco Targets Ther.2017;(10):4635-4643
Abstract: Clear-cell renal cell carcinoma (ccRCC) is a heterogeneous disease with a different clinical behavior and response to targeted therapies. Differences in hypoxia-inducible factor (HIF) expression have been used to classify von Hippel-Lindau gene (VHL)-deficient ccRCC tumors. c-Myc may be driving proliferation in HIF-2α-expressing tumors in a growth factor-independent manner.
PMID: 29033582
URI: https://hdl.handle.net/20.500.12530/30080
Rights: openAccess
ISSN: 1178-6930
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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