Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study.

Buti, María; Manzano, María L; Morillas, Rosa M; García-Retortillo, Montserrat; Martín, Leticia; Prieto, Martín; Gutiérrez, María L; Suárez, Emilio; Gómez Rubio, Mariano; López, Javier; Castillo, Pilar; Rodríguez, Manuel; Zozaya, José M; Simón, Miguel A; Morano, Luis E; Calleja, José L; Yébenes, María; Esteban, Rafael

Document types check

Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/30465

Title:	Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study.
Authors:	Buti, María Manzano, María L Morillas, Rosa M García-Retortillo, Montserrat Martín, Leticia Prieto, Martín Gutiérrez, María L Suárez, Emilio Gómez Rubio, Mariano López, Javier Castillo, Pilar Rodríguez, Manuel Zozaya, José M Simón, Miguel A Morano, Luis E Calleja, José L Yébenes, María Esteban, Rafael View more
Mesh:	Aged Aged, 80 and over Antineoplastic Agents Antiviral Agents Female Hepatitis B Hepatitis B virus Humans Leukemia Male Middle Aged Post-Exposure Prophylaxis Rituximab Serologic Tests Tenofovir View more
Issue Date:	2017
Citation:	PLoS ONE.2017;(12)9:e0184550
Abstract:	Hepatitis B virus (HBV) reactivation in patients with resolved HBV infection (HBsAg negative, antiHBc positive) is uncommon, but potentially fatal. The role of HBV prophylaxis in this setting is uncertain. The aim of this study was to compare the efficacy of tenofovir disoproxil fumarate (TDF) prophylaxis versus close monitoring in antiHBc-positive, HBsAg-negative patients under treatment with rituximab (RTX)-based regimens for hematologic malignancy.
PMID:	28898281
URI:	https://hdl.handle.net/20.500.12530/30465
Rights:	openAccess
Appears in Collections:	Hospitales > H. U. Fundación Alcorcón > Artículos Hospitales > H. U. 12 de Octubre > Artículos Fundaciones e Institutos de Investigación > IIS H. U. Getafe > Artículos Hospitales > H. U. Puerta de Hierro Majadahonda > Artículos Fundaciones e Institutos de Investigación > IIS H. U. 12 de Octubre > Artículos Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos Fundaciones e Institutos de Investigación > IIS H. U. Puerta de Hierro-Segovia de Arana > Artículos

Files in This Item:

File	Description	Size	Format
PMC5595327.pdf		1.66 MB	Adobe PDF	View/Open

Show full item record