Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/31002
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGonzález-de-Olano, David
dc.contributor.authorÁlvarez-Twose, Iván
dc.date.accessioned2019-06-28T16:27:35Z-
dc.date.available2019-06-28T16:27:35Z-
dc.date.issued2017
dc.identifier.citationFront Immunol.2017;(8):792
dc.identifier.issn1664-3224
dc.identifier.urihttps://hdl.handle.net/20.500.12530/31002-
dc.description.abstractThe prevalence of anaphylaxis among patients with clonal mast cell disorders (MCD) is clearly higher comparing to the general population. Due to a lower frequency of symptoms outside of acute episodes, clonal MCD in the absence of skin lesions might sometimes be difficult to identify which may lead to underdiagnosis, and anaphylaxis is commonly the presenting symptom in these patients. Although the release of mast cell (MC) mediators upon MC activation might present with a wide variety of symptoms, particular clinical features typically characterize MC mediator release episodes in patients with clonal MCD without skin involvement. Final diagnosis requires a bone marrow study, and it is recommended that this should be done in reference centers. In this article, we address the main triggers for anaphylaxis, risk factors, clinical presentation, diagnosis, and management of patients with MC activation syndromes (MCASs), with special emphasis on clonal MCAS [systemic mastocytosis and mono(clonal) MC activations syndromes].
dc.language.isoeng
dc.rightsopenAccess-
dc.subjectanaphylaxis
dc.subjectclonal
dc.subjectmast cell
dc.subjectmast cell activation syndrome
dc.subjectmastocytosis
dc.titleInsights in Anaphylaxis and Clonal Mast Cell Disorders.
dc.typeArtículo
dc.identifier.pubmedID28740494
dc.format.volume8
dc.format.page792
dc.identifier.journalFrontiers in immunology
dc.identifier.doi10.3389/fimmu.2017.00792
dc.identifier.pmcPMC5502410
dc.pubmedtypeJournal Article
dc.pubmedtypeReview
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

Files in This Item:
File Description SizeFormat 
PMC5502410.pdf214.57 kBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.