FXa inhibition by rivaroxaban modifies mechanisms associated with the pathogenesis of human abdominal aortic aneurysms.

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/31026

Title:	FXa inhibition by rivaroxaban modifies mechanisms associated with the pathogenesis of human abdominal aortic aneurysms.
Authors:	Moñux, Guillermo Zamorano-León, Jose J Marqués, Pablo Sopeña, Bernardo García-García, J M Laich de Koller, G Calvo-Rico, Bibiana García-Fernandez, Miguel A Serrano, J López-Farré, Antonio View more
Keywords:	NADPH oxidase factor Xa human abdominal aortic aneurysms inflammation oxidative stress thrombus View more
Mesh:	Adult Aged Anti-Inflammatory Agents Antioxidants Aortic Aneurysm, Abdominal Biomarkers Blood Coagulation Case-Control Studies Factor Xa Inhibitors Female Humans In Vitro Techniques Inflammation Mediators Interleukin-6 Male Matrix Metalloproteinase 9 Middle Aged NADPH Oxidase 2 Nitric Oxide Synthase Type II Oxidative Stress Phosphoproteins Rivaroxaban View more
Issue Date:	2017
Citation:	Br J Clin Pharmacol.2017 12;(83)12:2661-2670
Abstract:	To evaluate if rivaroxaban, an oral factor Xa (FXa) inhibitor, could modify the expression in vitro of inflammatory and oxidative stress biomarkers in abdominal aortic aneurysmal (AAA) sites showing intraluminal thrombus.
PMID:	28735510
URI:	https://hdl.handle.net/20.500.12530/31026
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos

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