Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/32325
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dc.contributor.authorRomero-Maté, Alberto-
dc.contributor.authorGarcía-Donoso, Carmen-
dc.contributor.authorHernández-Núñez, Almudena-
dc.contributor.authorMartínez-Morán, Cristina-
dc.contributor.authorMoreno Torres, Amalia-
dc.contributor.authorBorbujo, Jesus-
dc.date.accessioned2019-06-28T16:59:32Z-
dc.date.available2019-06-28T16:59:32Z-
dc.date.issued2017-01-15-
dc.identifier.citationDermatol. Online J..2017 Jan;(23)1:-
dc.identifier.urihttps://hdl.handle.net/20.500.12530/32325-
dc.description.abstractWe report a 52-year old woman with a 28-year historyof disfiguring facial discoid lupus erythematosus(DLE), persistent despite both classical therapiesand rituximab. Ustekinumab 45 mg was started incombination with methotrexate and intralesionalcorticosteroids. Methotrexate and intralesionalcorticosteroids were withdrawn 30 months later andustekinumab maintained as monotherapy. Fortyeight months later stable improvement was achievedwithout side effects. Only nine patients with cutaneouslupus erythematosus (CLE) treated with ustekinumabhave been reported to date. Ustekinumab could be apromising alternative in severe and recalcitrant casesof CLE. Possibly, the Th17-inflammation pathway isplaying a role in these patients.-
dc.language.isoeng-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/-
dc.subject.meshAdrenal Cortex Hormones-
dc.subject.meshDermatologic Agents-
dc.subject.meshFacial Dermatoses-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshImmunologic Factors-
dc.subject.meshImmunosuppressive Agents-
dc.subject.meshInjections, Intralesional-
dc.subject.meshLupus Erythematosus, Discoid-
dc.subject.meshMethotrexate-
dc.subject.meshMiddle Aged-
dc.subject.meshRituximab-
dc.subject.meshTreatment Failure-
dc.subject.meshUstekinumab-
dc.subject.meshRituximab-
dc.titleSuccessful treatment of recalcitrant discoid lupus erythematosus with ustekinumab.-
dc.typeArtículo-
dc.identifier.pubmedID28329473-
dc.format.volume23-
dc.identifier.e-issn1087-2108-
dc.identifier.journalDermatology online journal-
dc.contributor.authoraffiliationHospital Universitario de Fuenlabrada-
dc.format.number1-
dc.subject.decsUstekinumab-
dc.subject.decsInsuficiencia del Tratamiento-
dc.subject.decsMetotrexato-
dc.subject.decsLupus Eritematoso Discoide-
dc.pubmedtypeCase Reports-
dc.pubmedtypeJournal Article-
Appears in Collections:Hospitales > H. U. de Fuenlabrada > Artículos

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