Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/32358
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dc.contributor.authorRallón, Norma
dc.contributor.authorGarcía, Marcial
dc.contributor.authorGarcía-Samaniego, Javier
dc.contributor.authorRodríguez, Noelia
dc.contributor.authorCabello, Alfonso
dc.contributor.authorRestrepo, Clara
dc.contributor.authorÁlvarez, Beatriz
dc.contributor.authorGarcía, Rosa
dc.contributor.authorGórgolas, Miguel
dc.contributor.authorBenito, José M
dc.date.accessioned2019-06-28T17:00:00Z-
dc.date.available2019-06-28T17:00:00Z-
dc.date.issued2017
dc.identifier.citationPLoS ONE.2017;(12)3:e0173943
dc.identifier.urihttps://hdl.handle.net/20.500.12530/32358-
dc.description.abstractThere are several contributors to HIV-pathogenesis or insufficient control of the infection. However, whether HIV/HCV-coinfected population exhibits worst evolution of HIV-pathogenesis remains unclear. Recently, some markers of immune exhaustion have been proposed as preferentially upregulated on T-cells during HIV-infection. Herein, we have analyzed T-cell exhaustion together with several other contributors to HIV-pathogenesis that could be affected by HCV-coinfection.
dc.language.isoeng
dc.rightsopenAccess-
dc.subject.meshAdult
dc.subject.meshCD4-Positive T-Lymphocytes
dc.subject.meshCD8-Positive T-Lymphocytes
dc.subject.meshCase-Control Studies
dc.subject.meshCoinfection
dc.subject.meshCross-Sectional Studies
dc.subject.meshDisease Progression
dc.subject.meshFemale
dc.subject.meshHIV Infections
dc.subject.meshHepatitis C, Chronic
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshMultivariate Analysis
dc.subject.meshStatistics, Nonparametric
dc.subject.meshViral Load
dc.titleHCV coinfection contributes to HIV pathogenesis by increasing immune exhaustion in CD8 T-cells.
dc.typeArtículo
dc.identifier.pubmedID28323897
dc.format.volume12
dc.format.pagee0173943
dc.identifier.e-issn1932-6203
dc.identifier.journalPloS one
dc.identifier.doi10.1371/journal.pone.0173943
dc.format.number3
dc.identifier.pmcPMC5360268
dc.pubmedtypeJournal Article
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos
Hospitales > H. U. La Paz > Artículos

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