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dc.contributor.authorHernando, Victoria
dc.contributor.authorAlejos, Belen
dc.contributor.authorMontero, Marta
dc.contributor.authorPérez-Elias, MJesús
dc.contributor.authorBlanco, José Ramón
dc.contributor.authorGiner, Livia
dc.contributor.authorGómez-Sirvent, Juan Luis
dc.contributor.authorIribarren, Jose Antonio
dc.contributor.authorBernal, Enrique
dc.contributor.authorBolumar, Francisco
dc.identifier.citationMedicine (Baltimore).2017 Feb;(96)5:e5991
dc.description.abstractThe aim of this study is to examine the reproductive history of human immunodeficiency virus (HIV)-positive women, before and after HIV diagnosis, to describe the characteristics of women with pregnancies after HIV diagnosis, and to assess the prevalence of mother-to-child transmission.A cross-sectional study was performed among women within reproductive ages (18-49) selected from the cohort in the Spanish AIDS Research Network (CoRIS). A descriptive analysis of the pregnancy outcomes was made according to women's serostatus at the moment of pregnancy and association of women's characteristics with having pregnancy after HIV diagnosis was evaluated using logistic regression models.Overall, 161 women were interviewed; of them, 86% had been pregnant at least once and 39% after HIV diagnosis. There were 347 pregnancies, 29% of them occurred after HIV diagnosis and in these, 20% were miscarriages and 29% were voluntary termination of pregnancy. There were 3 cases of mother-to-child transmission among the 56 children born from HIV-positive mothers; in these cases, women were diagnosed during delivery. Having a pregnancy after HIV diagnosis was more likely when the younger women were at the time of diagnosis: odds ratio (OR) = 1.29 (95% confidence interval 0.40-4.17) for 25 to 29 years old, OR = 0.59 (0.15-2.29) for 30 to 34 years old, OR = 0.14 (0.03-0.74) for ≥35 years old, compared with those <25 years at diagnosis, who were diagnosed for ≥5 years (OR = 5.27 [1.71-16.18]), who received antiretroviral treatment at some point (OR = 9.38 [1.09-80.45]), and who received information on reproductive health (OR = 4.32 [1.52-12.26]).An important number of pregnancies occurred after HIV diagnosis, reflecting a desire for motherhood in these women. Reproductive and sexual health should be tackled in medical follow-ups.
dc.subject.meshCross-Sectional Studies
dc.subject.meshHIV Infections
dc.subject.meshHIV Seropositivity
dc.subject.meshInfectious Disease Transmission, Vertical
dc.subject.meshMiddle Aged
dc.subject.meshOdds Ratio
dc.subject.meshPregnancy Complications, Infectious
dc.subject.meshPregnancy Outcome
dc.subject.meshYoung Adult
dc.subject.meshReproductive History
dc.titleReproductive history before and after HIV diagnosis: A cross-sectional study in HIV-positive women in Spain.
dc.pubmedtypeJournal Article
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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