Photoreceptor preservation induced by intravitreal controlled delivery of GDNF and GDNF/melatonin in rhodopsin knockout mice.

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/34407

Title:	Photoreceptor preservation induced by intravitreal controlled delivery of GDNF and GDNF/melatonin in rhodopsin knockout mice.
Authors:	García-Caballero, Cristina Lieppman, Burke Arranz-Romera, Alicia Molina-Martínez, Irene T Bravo-Osuna, Irene Young, Michael Baranov, Petr Herrero-Vanrell, Rocío View more
Mesh:	Animals Delayed-Action Preparations Disease Models, Animal Drug Combinations Drug Compounding Drug Liberation Electroretinography Gene Expression Glial Cell Line-Derived Neurotrophic Factor Intravitreal Injections Melatonin Mice Mice, Knockout Microspheres Polylactic Acid-Polyglycolic Acid Copolymer Retina Retinal Degeneration Rhodopsin Vitamin E Vitreous Body View more
Issue Date:	2018
Citation:	Mol. Vis..2018;(24):733-745
Abstract:	To evaluate the potential of a poly(lactic-co-glycolic acid) (PLGA)-based slow release formulation of glial cell line-derived neurotrophic factor (GDNF) alone or in combination with melatonin to rescue photoreceptors in a mouse model of retinal degeneration.
PMID:	30581280
URI:	https://hdl.handle.net/20.500.12530/34407
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos

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