C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation.

Document types check

Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/34452

Title:	C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation.
Authors:	Ortiz-Rivero, Sara Baquero, Cristina Hernández-Cano, Luis Roldán-Etcheverry, Juan José Gutiérrez-Herrero, Sara Fernández-Infante, Cristina Martín-Granado, Víctor Anguita, Eduardo de Pereda, José María Porras, Almudena Guerrero, Carmen View more
Keywords:	C3G Differentiation Megakaryocyte Megakaryopoiesis Platelet View more
Mesh:	Adipogenesis Blood Platelets Cell Line, Tumor Guanine Nucleotide-Releasing Factor 2 Humans Megakaryocytes Ploidies Cell Differentiation View more
Issue Date:	2018
Citation:	Cell Commun. Signal.2018 12;(16)1:101
Abstract:	Megakaryopoiesis allows platelet formation, which is necessary for coagulation, also playing an important role in different pathologies. However, this process remains to be fully characterized. C3G, an activator of Rap1 GTPases, is involved in platelet activation and regulates several differentiation processes.
PMID:	30567575
URI:	https://hdl.handle.net/20.500.12530/34452
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos

Files in This Item:

File	Description	Size	Format
PMC6299959.pdf		5.62 MB	Adobe PDF	View/Open