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|Title:||C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation.|
Cell Line, Tumor
Guanine Nucleotide-Releasing Factor 2
|Citation:||Cell Commun. Signal.2018 12;(16)1:101|
|Abstract:||Megakaryopoiesis allows platelet formation, which is necessary for coagulation, also playing an important role in different pathologies. However, this process remains to be fully characterized. C3G, an activator of Rap1 GTPases, is involved in platelet activation and regulates several differentiation processes.|
|Appears in Collections:||Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos|
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