Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/36711
Title: Immune monitoring after pediatric liver transplantation - the prospective ChilSFree cohort study.
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Issue Date: 16-May-2018
Citation: BMC Gastroenterol.2018 May;(18)1:63
Abstract: Although trough levels of immunosuppressive drugs are largely used to monitor immunosuppressive therapy after solid organ transplantation, there is still no established tool that allows for a validated assessment of functional degree of immunosuppression or the identification of clinically relevant over- or under-immunosuppression, depending on graft homeostasis. Reliable non-invasive markers to predict biopsy proven acute rejection (BPAR) do not exist. Literature data suggest that longitudinal measurements of immune markers might be predictive of BPAR, but data in children are scarce. We therefore propose an observational prospective cohort study focusing on immune monitoring in children after liver transplantation. We aim to describe immune function in a cohort of children before and during the first year after liver transplantation and plan to investigate how the immune function profile is associated with clinical and laboratory findings.
PMID: 29769027
URI: https://hdl.handle.net/20.500.12530/36711
Rights: openAccess
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos
Hospitales > H. U. La Paz > Artículos

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