Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers.

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/37612

Title:	Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers.
Authors:	Benito, José M Ortiz, María C León, Agathe Sarabia, Luis A Ligos, José Manuel Montoya, María Garcia, Marcial Ruiz-Mateos, Ezequiel Palacios, Rosario Cabello, Alfonso Restrepo, Clara Rodriguez, Carmen Del Romero, Jorge Leal, Manuel Muñoz-Fernández, María A Alcamí, José García, Felipe Górgolas, Miguel Rallón, Norma View more
Keywords:	CD4 T-cell loss CD8 exhaustion Class modeling Elite controllers T-cell homeostatic parameters View more
Mesh:	Adult CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes Case-Control Studies Disease Progression Female HIV Infections Humans Male Middle Aged Homeostasis View more
Issue Date:	2018
Citation:	BMC Med.2018 02;(16)1:30
Abstract:	Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mechanisms that may be operating in those patients experiencing loss of immunological control.
PMID:	29490663
URI:	https://hdl.handle.net/20.500.12530/37612
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > IIS H. General U. Gregorio Marañón > Artículos Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos

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