Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/37612
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dc.contributor.authorBenito, José M
dc.contributor.authorOrtiz, María C
dc.contributor.authorLeón, Agathe
dc.contributor.authorSarabia, Luis A
dc.contributor.authorLigos, José Manuel
dc.contributor.authorMontoya, María
dc.contributor.authorGarcia, Marcial
dc.contributor.authorRuiz-Mateos, Ezequiel
dc.contributor.authorPalacios, Rosario
dc.contributor.authorCabello, Alfonso
dc.contributor.authorRestrepo, Clara
dc.contributor.authorRodriguez, Carmen
dc.contributor.authorDel Romero, Jorge
dc.contributor.authorLeal, Manuel
dc.contributor.authorMuñoz-Fernández, María A
dc.contributor.authorAlcamí, José
dc.contributor.authorGarcía, Felipe
dc.contributor.authorGórgolas, Miguel
dc.contributor.authorRallón, Norma
dc.date.accessioned2019-06-28T18:35:25Z-
dc.date.available2019-06-28T18:35:25Z-
dc.date.issued2018
dc.identifier.citationBMC Med.2018 02;(16)1:30
dc.identifier.urihttps://hdl.handle.net/20.500.12530/37612-
dc.description.abstractDespite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mechanisms that may be operating in those patients experiencing loss of immunological control.
dc.language.isoeng
dc.rightsopenAccess-
dc.subjectCD4 T-cell loss
dc.subjectCD8 exhaustion
dc.subjectClass modeling
dc.subjectElite controllers
dc.subjectT-cell homeostatic parameters
dc.subject.meshAdult
dc.subject.meshCD4-Positive T-Lymphocytes
dc.subject.meshCD8-Positive T-Lymphocytes
dc.subject.meshCase-Control Studies
dc.subject.meshDisease Progression
dc.subject.meshFemale
dc.subject.meshHIV Infections
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshHomeostasis
dc.titleClass-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers.
dc.typeArtículo
dc.identifier.pubmedID29490663
dc.format.volume16
dc.format.page30
dc.identifier.e-issn1741-7015
dc.identifier.journalBMC medicine
dc.identifier.doi10.1186/s12916-018-1026-6
dc.format.number1
dc.identifier.pmcPMC5830067
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. General U. Gregorio Marañón > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos

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