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|Title:||Multiplatform plasma fingerprinting in cancer cachexia: a pilot observational and translational study.|
|Citation:||J Cachexia Sarcopenia Muscle.2018 04;(9)2:348-357|
|Abstract:||Cachexia is a metabolic syndrome that affects up to 50-80% of cancer patients. The pathophysiology is characterized by a variable combination of reduced food intake and abnormal metabolism, including systemic inflammation and negative protein and energy balance. Despite its high clinical significance, defined diagnostic criteria and established therapeutic strategies are lacking. The 'omics' technologies provide a global view of biological systems. We hypothesize that blood-based metabolomics might identify findings in cachectic patients that could provide clues to gain knowledge on its pathophysiology, and eventually postulate new therapeutic strategies.|
|Appears in Collections:||Fundaciones e Institutos de Investigación > IIS H. U. 12 de Octubre > Artículos|
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