Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/38310
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dc.contributor.authorEscribano Montaner, Amparo
dc.contributor.authorGarcía de Lomas, Juan
dc.contributor.authorVilla Asensi, José Ramón
dc.contributor.authorAsensio de la Cruz, Oscar
dc.contributor.authorde la Serna Blázquez, Olga
dc.contributor.authorSantiago Burruchaga, Mikel
dc.contributor.authorMondéjar López, Pedro
dc.contributor.authorTorrent Vernetta, Alba
dc.contributor.authorFeng, Yang
dc.contributor.authorVan Dyke, Melissa K
dc.contributor.authorReyes, Janet
dc.contributor.authorGarcia-Corbeira, Pilar
dc.contributor.authorTalarico, Carla A
dc.date.accessioned2019-06-28T18:48:55Z-
dc.date.available2019-06-28T18:48:55Z-
dc.date.issued2018-02
dc.identifier.citationEur. J. Pediatr..2018 Feb;(177)2:181-192
dc.identifier.urihttps://hdl.handle.net/20.500.12530/38310-
dc.description.abstractThis cross-sectional study assessed the prevalence of bacteria isolated from Spanish children with suspected chronic lower respiratory tract infection (LRTI) for whom bronchoalveolar lavage (BAL) was indicated. BAL fluid (BALF) was collected from 191 children (aged ≥ 6 months to < 6 years, with persistent or recurrent respiratory symptoms, non-responders to usual treatment) and cultured. Nasopharyngeal swabs (NPSs) were also obtained and cultured to assess concordance of BALF and NPS findings in the same patient. Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis were identified from BALF with a bacterial load indicative of infection (> 104 colony-forming units/mL) in 10.5, 8.9, and 6.3% of children, respectively. Clinical characteristics were similar among participants, regardless of positivity status for any of the bacteria. Approximately 26% of pneumococcal isolates were PCV13 serotypes, and 96% of H. influenzae isolates were non-typeable (NTHi). Concordance between BALF and NPS isolates was 51.0% for S. pneumoniae, 52.1% for H. influenzae, and 22.0% for M. catarrhalis.
dc.language.isoeng
dc.rightsopenAccess-
dc.subjectBronchoalveolar lavage
dc.subjectChildren
dc.subjectChronic lower respiratory tract infection
dc.subjectNasopharyngeal colonization
dc.subjectNon-typeable Haemophilus influenzae
dc.subjectStreptococcus pneumoniae
dc.subject.meshBronchoalveolar Lavage
dc.subject.meshBronchoalveolar Lavage Fluid
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshChronic Disease
dc.subject.meshCross-Sectional Studies
dc.subject.meshFemale
dc.subject.meshHaemophilus Infections
dc.subject.meshHaemophilus influenzae
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshMale
dc.subject.meshMoraxella (Branhamella) catarrhalis
dc.subject.meshMoraxellaceae Infections
dc.subject.meshPneumococcal Infections
dc.subject.meshPneumonia, Bacterial
dc.subject.meshPneumonia, Pneumococcal
dc.subject.meshSpain
dc.titleBacteria from bronchoalveolar lavage fluid from children with suspected chronic lower respiratory tract infection: results from a multi-center, cross-sectional study in Spain.
dc.typeArtículo
dc.identifier.pubmedID29285648
dc.format.volume177
dc.format.page181-192
dc.identifier.e-issn1432-1076
dc.identifier.journalEuropean journal of pediatrics
dc.identifier.doi10.1007/s00431-017-3044-3
dc.format.number2
dc.identifier.pmcPMC5758651
dc.pubmedtypeClinical Trial
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
Appears in Collections:Fundaciones e Institutos de Investigación > FIB H. Infantil U. Niño Jesús > Artículos
Fundaciones e Institutos de Investigación > IIS H. U. La Paz > Artículos
Hospitales > H. U. La Paz > Artículos

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