Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia.

Forero-Castro, Maribel; Robledo, Cristina; Benito, Rocío; Bodega-Mayor, Irene; Rapado, Inmaculada; Hernández-Sánchez, María; Abaigar, María; Maria Hernández-Sánchez, Jesús; Quijada-Álamo, Miguel; María Sánchez-Pina, José; Sala-Valdés, Mónica; Araujo-Silva, Fernanda; Kohlmann, Alexander; Luis Fuster, José; Arefi, Maryam; de Las Heras, Natalia; Riesco, Susana; Rodríguez, Juan N; Hermosín, Lourdes; Ribera, Jordi; Camos Guijosa, Mireia; Ramírez Orellana, Manuel; de Heredia Rubio, Cristina Díaz; Barragán, Eva; Martínez, Joaquín; Ribera, José M; Fernández-Ruiz, Elena; Hernández-Rivas, Jesús-María

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/39434

Title:	Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia.
Authors:	Forero-Castro, Maribel Robledo, Cristina Benito, Rocío Bodega-Mayor, Irene Rapado, Inmaculada Hernández-Sánchez, María Abaigar, María Maria Hernández-Sánchez, Jesús Quijada-Álamo, Miguel María Sánchez-Pina, José Sala-Valdés, Mónica Araujo-Silva, Fernanda Kohlmann, Alexander Luis Fuster, José Arefi, Maryam de Las Heras, Natalia Riesco, Susana Rodríguez, Juan N Hermosín, Lourdes Ribera, Jordi Camos Guijosa, Mireia Ramírez Orellana, Manuel de Heredia Rubio, Cristina Díaz Barragán, Eva Martínez, Joaquín Ribera, José M Fernández-Ruiz, Elena Hernández-Rivas, Jesús-María View more
Mesh:	Adolescent Adult Aged Aged, 80 and over B-Lymphocytes Biomarkers, Tumor Child Child, Preschool Disease-Free Survival Female Gene Expression Regulation, Neoplastic High-Throughput Nucleotide Sequencing Humans Infant Janus Kinase 2 Male Middle Aged Mutation Precursor Cell Lymphoblastic Leukemia-Lymphoma Prognosis Receptors, Cytokine Treatment Outcome Tumor Suppressor Protein p53 View more
Issue Date:	11-Jul-2017
Citation:	Br. J. Cancer.2017 Jul;(117)2:256-265
Abstract:	In B-cell precursor acute lymphoblastic leukaemia (B-ALL), the identification of additional genetic alterations associated with poor prognosis is still of importance. We determined the frequency and prognostic impact of somatic mutations in children and adult cases with B-ALL treated with Spanish PETHEMA and SEHOP protocols.
PMID:	28557976
URI:	https://hdl.handle.net/20.500.12530/39434
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > FIB H. Infantil U. Niño Jesús > Artículos Hospitales > H. U. 12 de Octubre > Artículos Fundaciones e Institutos de Investigación > IIS H. U. La Princesa > Artículos Hospitales > H. U. Clínico San Carlos > Artículos Fundaciones e Institutos de Investigación > IIS H. U. 12 de Octubre > Artículos

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