Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/41827
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dc.contributor.authorMarquez, Diego F
dc.contributor.authorRuiz-Hurtado, Gema
dc.contributor.authorRuilope, Luis
dc.date.accessioned2019-08-02T11:37:28Z-
dc.date.available2019-08-02T11:37:28Z-
dc.date.issued2017
dc.identifier.citationF1000Res.2017;(6):611
dc.identifier.issn2046-1402
dc.identifier.urihttps://hdl.handle.net/20.500.12530/41827-
dc.description.abstractArterial hypertension and chronic kidney disease (CKD) are intimately related. The control of blood pressure (BP) levels is strongly recommended in patients with CKD in order to protect the kidney against the accompanying elevation in global cardiovascular (CV) risk. Actually, the goal BP in patients with CKD involves attaining values <140/90 mmHg except if albuminuria is present. In this case, it is often recommended to attain values <130/80 mmHg, although some guidelines still recommend <140/90 mmHg. Strict BP control to values of systolic BP around 120 mmHg was recently shown to be safe in CKD according to data from the SPRINT trial, albeit more data confirming this benefit are required. Usually, combination therapy initiated with an angiotensin receptor blocker (ARB) or angiotensin-converting enzyme inhibitor (ACEi) and commonly followed by the addition of a calcium channel blocker and a diuretic is needed. Further studies are required as well as new drugs in particular after the positive data obtained from new oral anti-diabetic drugs.
dc.language.isoeng
dc.rightsopenAccess-
dc.subjectCKD
dc.subjectantihypertensives
dc.subjectarterial hypertension
dc.subjectchronic kidney disease
dc.subjectkidney disease
dc.titleThe impact of antihypertensives on kidney disease.
dc.typeArtículo
dc.identifier.pubmedID28529721
dc.format.volume6
dc.format.page611
dc.identifier.journalF1000Research
dc.identifier.doi10.12688/f1000research.9916.1
dc.identifier.pmcPMC5414822
dc.pubmedtypeJournal Article
dc.pubmedtypeReview
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. 12 de Octubre > Artículos

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