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Title: Smartphone confocal microscopy for imaging cellular structures in human skin in vivo.
Keywords: (170.1790) Confocal microscopy
(170.1870) Dermatology
Issue Date: 1-Apr-2018
Citation: Biomed Opt Express.2018 Apr;(9)4:1906-1915
Abstract: We report development of a low-cost smartphone confocal microscope and its first demonstration of in vivo human skin imaging. The smartphone confocal microscope uses a slit aperture and diffraction grating to conduct two-dimensional confocal imaging without using any beam scanning devices. Lateral and axial resolutions of the smartphone confocal microscope were measured as 2 and 5 µm, respectively. In vivo confocal images of human skin revealed characteristic cellular structures, including spinous and basal keratinocytes and papillary dermis. Results suggest that the smartphone confocal microscope has a potential to examine cellular details in vivo and may help disease diagnosis in resource-poor settings, where conducting standard histopathologic analysis is challenging.
PMID: 29675328
Rights: openAccess
ISSN: 2156-7085
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. Ramón y Cajal > Artículos

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