Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/54064
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dc.contributor.authorJohnson, Robert W
dc.contributor.authorAlvarez-Pasquin, Marie-José
dc.contributor.authorBijl, Marc
dc.contributor.authorFranco, Elisabetta
dc.contributor.authorGaillat, Jacques
dc.contributor.authorClara, João G
dc.contributor.authorLabetoulle, Marc
dc.contributor.authorMichel, Jean-Pierre
dc.contributor.authorNaldi, Luigi
dc.contributor.authorSanmarti, Luis S
dc.contributor.authorWeinke, Thomas
dc.date.accessioned2020-05-12T07:40:45Z-
dc.date.available2020-05-12T07:40:45Z-
dc.date.issued2015-07
dc.identifier.citationTher Adv Vaccines.2015 Jul;(3)4:109-20
dc.identifier.issn2051-0136
dc.identifier.urihttps://hdl.handle.net/20.500.12530/54064-
dc.description.abstractHerpes zoster (HZ) is primarily a disease of nerve tissue but the acute and longer-term manifestations require multidisciplinary knowledge and involvement in their management. Complications may be dermatological (e.g. secondary bacterial infection), neurological (e.g. long-term pain, segmental paresis, stroke), ophthalmological (e.g. keratitis, iridocyclitis, secondary glaucoma) or visceral (e.g. pneumonia, hepatitis). The age-related increased incidence of HZ and its complications is thought to be a result of the decline in cell-mediated immunity (immunosenescence), higher incidence of comorbidities with age and social-environmental changes. Individuals who are immunocompromised as a result of disease or therapy are also at increased risk, independent of age. HZ and its complications (particularly postherpetic neuralgia) create a significant burden for the patient, carers, healthcare systems and employers. Prevention and treatment of HZ complications remain a therapeutic challenge despite recent advances. This is an overview of the multidisciplinary implications and management of HZ in which the potential contribution of vaccination to reducing the incidence HZ and its complications are also discussed.
dc.language.isoeng
dc.subjectherpes zoster
dc.subjectherpes zoster diagnosis
dc.subjectherpes zoster treatment
dc.subjectherpes zoster vaccination
dc.subjectmultidisciplinary management
dc.subjectpostherpetic neuralgia
dc.titleHerpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective.
dc.typeJournal Article
dc.typeReview
dc.identifier.pubmedID26478818
dc.format.volume3
dc.format.page109-20
dc.identifier.journalTherapeutic advances in vaccines
dc.identifier.doi10.1177/2051013615599151
dc.format.number4
dc.identifier.pmcPMC4591524
Appears in Collections:Centros de Atención Primaria > Artículos

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