Immuno-priming durvalumab with bevacizumab in HER2-negative advanced breast cancer: a pilot clinical trial

quintela-fandino, miguel; Holgado, Esther; Manso, Luis; Morales, Serafín; Bermejo, Begoña; Colomer, Ramón; Apala, Juan V; Blanco, Raquel; Muñoz, Manuel; Caleiras, Eduardo; Iranzo, Vega; Martínez, Mario; Domínguez, Orlando; Hornedo, Javier; González-Cortijo, Lucía; Cortés, Javier; Gasol Cudos, Ariadna; Malon, Diego; Lopez-Alonso, Antonio; Moreno-Ortíz, María C; Mouron, Silvana; Mañes, Santos

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/54354

Title:	Immuno-priming durvalumab with bevacizumab in HER2-negative advanced breast cancer: a pilot clinical trial
Authors:	quintela-fandino, miguel Holgado, Esther Manso, Luis Morales, Serafín Bermejo, Begoña Colomer, Ramón Apala, Juan V Blanco, Raquel Muñoz, Manuel Caleiras, Eduardo Iranzo, Vega Martínez, Mario Domínguez, Orlando Hornedo, Javier González-Cortijo, Lucía Cortés, Javier Gasol Cudos, Ariadna Malon, Diego Lopez-Alonso, Antonio Moreno-Ortíz, María C Mouron, Silvana Mañes, Santos View more
Filiation:	Servicio de Oncología. Hospital Universitario de Fuenlabrada
Keywords:	Bevacizumab Durvalumab HER2-negative breast cancer Immuno-priming Vascular normalization View more
Mesh:	Bevacizumab Antibodies, Monoclonal Triple Negative Breast Neoplasms Breast neoplasms Antineoplastic Agents View more
Decs:	Antineoplásicos Neoplasias de la Mama Neoplasias de la Mama Triple Negativas Bevacizumab View more
Issue Date:	2020
Citation:	Breast Cancer Res.2020 11;(22)1:124
Abstract:	Preclinical research suggests that the efficacy of immune checkpoint inhibitors in breast cancer can be enhanced by combining them with antiangiogenics, particularly in a sequential fashion. We sought to explore the efficacy and biomarkers of combining the anti-PD-L1 durvalumab plus the antiangiogenic bevacizumab after bevacizumab monotherapy for advanced HER2-negative breast cancer.
PMID:	33176887
URI:	https://hdl.handle.net/20.500.12530/54354
Rights:	info:eu-repo/semantics/openAccess
Appears in Collections:	Hospitales > H. U. de Fuenlabrada > Artículos

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