Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/54382
Title: Incidence, clinical characteristics and management of inflammatory bowel disease in Spain: large-scale epidemiological study
Authors: 
Chaparro, María
Garre, Ana
Núñez Ortiz, Andrea
Diz-Lois Palomares, María Teresa
Rodríguez, Cristina
Riestra, Sabino
Vela, Milagros
Benítez, José Manuel
Fernández Salgado, Estela
Sánchez Rodríguez, Eugenia
Hernández, Vicent
Opio, Verónica
Nicolás, Isabel
Kutz, Marcos
Abraldes Bechiarelli, Alfredo
Gordillo, Jordi
Martínez-Cerezo, Francisco J
Ber Nieto, Yolanda
Torres Domínguez, Yolanda
Novella Durán, María Teresa
Rodríguez Mondéjar, Silvia
Roncero, Óscar
Kolle, Lilyan
Sabat, Miriam
Ledezma, Cesar
Iyo, Eduardo
Irisarri, Rebeca
Lluis, Laia
Blázquez Gómez, Isabel
Zapata, Eva María
Monrobel, Ana
José Alcalá, María
Martínez Pascual, Cristina
Montealegre, María
Mata, Laura
Galve, María Luisa
Hernández Camba, Alejandro
Hernández, Luis
Tejada, María
Mir, Alberto
Soler, Marta
Hervías, Daniel
Gómez-Valero, José Antonio
Barreiro-de Acosta, Manuel
Ferreiro-Iglesias, Rocío
Rodríguez-Artalejo, Fernando
García-Esquinas, Esther
Gisbert, Javier Pérez
EpidemIBD Study Group Of Geteccu
Martín-Arranz, María Dolores
Ponferrada Díaz, Ángel
Barrio, Jesús
Huguet, José María
Sicilia, Beatriz
Calvet, Xavier
Ginard, Daniel
Alonso-Abreu, Inmaculada
Fernández-Salazar, Luis
Varela Trastoy, Pilar
Rivero, Montserrat
Vera-Mendoza, Isabel
Vega, Pablo
Navarro, Pablo
Navarro-Llavat, Mercè
Sierra, Mónica
Cabriada, José Luis
Aguas, Mariam
Vicente, Raquel
Echarri, Ana
Gomollón, Fernando
Guerra Del Río, Elena
Piñero, Concepción
Casanova, María José
Spicakova, Katerina
Ortiz de Zarate, Jone
Torrella Cortés, Emilio
Gutiérrez, Ana
Calafat, Margalida
Alonso-Galán, Horacio
Hernández-Martínez, Álvaro
Marrero, José Miguel
Lorente Poyatos, Rufo
Martí Romero, Lidia
Robledo, Pilar
Bosch, Orencio
Jiménez, Nuria
Esteve Comas, María
Duque, José María
Fuentes Coronel, Ana María
Josefa Sampedro, Manuela
Sesé Abizanda, Eva
López Serrano, Pilar
Herreros Martínez, Belén
Pozzati, Liliana
Fernández Rosáenz, Hipólito
Crespo Suarez, Belén
Lucendo, Alfredo J
Muñoz Vicente, Margarita
Bermejo, Fernando
Ramírez Palanca, José Joaquín
Menacho, Margarita
Carmona, Amalia
Camargo, Raquel
Torra Alsina, Sandra
Maroto, Nuria
Sapiña, Amparo
Nerín de la Puerta, Juan
Castro, Elena
Marín-Jiménez, Ignacio
Botella, Belén
Cruz, Noelia
Forcelledo, José Luis F
Bouhmidi, Abdel
Castaño-Milla, Carlos
Filiation: Servicio de Digestivo. Hospital Universitario de Fuenlabrada
Keywords: 
Mesh: 
Decs: 
Issue Date: 29-Jun-2021
Citation: J Clin Med.2021 Jun;(10)13: 2885
Abstract: (1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery.
PMID: 34209680
URI: https://hdl.handle.net/20.500.12530/54382
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:Hospitales > H. U. de Fuenlabrada > Artículos
Hospitales > H. U. La Paz > Artículos

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