PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome

Estévez-García, Purificación; Castaño Pascual, Ángel; Martín, Ana C; López-Ríos, Fernando; Iglesias, Joaquín; Muñoz-Galván, Sandra; López-Calderero, Íker; Molina-Pinelo, Sonia; Pastor, María D; Carnero, Amancio; Paz-Ares, Luis; García-Carbonero, Rocío

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/54541

Title:	PDGFRα/β and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome
Authors:	Estévez-García, Purificación Castaño Pascual, Ángel Martín, Ana C López-Ríos, Fernando Iglesias, Joaquín Muñoz-Galván, Sandra López-Calderero, Íker Molina-Pinelo, Sonia Pastor, María D Carnero, Amancio Paz-Ares, Luis García-Carbonero, Rocío View more
Filiation:	Servicio de Anatomía Patológica. Hospital Universitario de Fuenlabrada
Mesh:	Aged Aged, 80 and over Alleles Cell Line, Tumor Colorectal Neoplasms Exons Female Genotype HT29 Cells Humans Male Middle Aged Mutation Polymorphism, Single Nucleotide Receptor, Platelet-Derived Growth Factor alpha Receptor, Platelet-Derived Growth Factor beta Vascular Endothelial Growth Factor Receptor-2 View more
Decs:	Alelos Receptor 2 de Factores de Crecimiento Endotelial Vascular Receptor beta de Factor de Crecimiento Derivado de Plaquetas Receptor alfa de Factor de Crecimiento Derivado de Plaquetas Polimorfismo de Nucleótido Simple Mutación Células HT29 Genotipo Exones Neoplasias Colorrectales View more
Issue Date:	12-Nov-2012
Publisher:	Springer Science and Business Media LLC
Citation:	Estévez García P, Castaño Pascual A, Martín AC, López Ríos F, Iglesias J, Muñoz Galván S, et al. PDGFRalpha/beta and VEGFR2 polymorphisms in colorectal cancer: incidence and implications in clinical outcome. BMC Cancer. 2012;12:514.
Abstract:	Angiogenesis plays an essential role in tumor growth and metastasis, and is a major target in cancer therapy. VEGFR and PDGFR are key players involved in this process. The purpose of this study was to assess the incidence of genetic variants in these receptors and its potential clinical implications in colorectal cancer (CRC).
PMID:	23146028
URI:	https://hdl.handle.net/20.500.12530/54541
Rights:	info:eu-repo/semantics/openAccess
Appears in Collections:	Hospitales > H. U. de Fuenlabrada > Artículos

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