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Title: Dermatosis ampollosa hemorrágica a distancia; dos nuevos casos por enoxaparina y revisión de la literatura
Filiation: Servicio de Dermatología. Hospital Universitario de Fuenlabrada.
Servicio de Anatomía Patológica. Hospital Universitario de Fuenlabrada.
Issue Date: Nov-2012
Publisher: Elsevier BV
Citation: Villanueva CA, Nájera L, Espinosa P, Borbujo J. Dermatosis ampollosa hemorrágica a distancia; dos nuevos casos por enoxaparina y revisión de la literatura. Actas Dermosifiliogr. 2012 Nov;103(9):816-9. English, Spanish. doi: 10.1016/ Epub 2012 Feb 15. PMID: 22341878.
Abstract: Enoxaparin is a low-molecular-weight heparin used in the prevention and treatment of pulmonary thromboembolism and other thrombotic disorders. The most common adverse reactions to enoxaparin are ecchymosis, skin necrosis, urticaria, angioedema, and eczema. The first 2 cases of bullous hemorrhagic dermatosis in areas distant from heparin injection sites were described in 2006. We present the cases of 2 men, aged 68 and 78 years, with progressive, advanced-stage lung cancer, who consulted with bullous hemorrhagic lesions without associated symptoms. Both patients reported that the lesions had appeared after initiation of heparin therapy at therapeutic doses. In our review of the literature, we found just 7 cases of heparin-induced bullous hemorrhagic dermatosis. We report a further 2 cases, caused by enoxaparin, in which treatment was continued and in which the lesions resolved in 2 to 3 weeks.
PMID: 22341878
Rights: info:eu-repo/semantics/openAccess
Atribución-NoComercial-SinDerivadas 3.0 España
ISSN: 0001-7310
Appears in Collections:Hospitales > H. U. de Fuenlabrada > Artículos

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