Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/55686
Title: SER recommendations on the use of biological drugs in primary Sjögren's syndrome.
Other Titles: Recomendaciones SER sobre la utilización de fármacos biológicos en el síndrome de Sjögren primario.
Authors: 
Keywords: 
Mesh: 
Issue Date: 23-Jan-2019
Citation: Reumatol Clin (Engl Ed).2019;(15)6:315-326
Abstract: To formulate SER recommendations for the use of biological agents in primary Sjögren's syndrome (pSS). Relevant clinical research questions were identified on the use of biological agents in pSS. The clinical questions were reformulated into 4PICO questions. A search strategy was designed and a review of the scientific evidence of studies published until May 2017 was carried out. The scientific evidence available was systematically reviewed. The overall level of scientific evidence was assessed using the SIGN evidence levels. After that, specific recommendations were made. Rituximab is recommended as the biological agent of choice for extraglandular manifestations refractory to conventional treatment. The use of anti-TNF agents is discouraged. The scientific evidence with belimumab and abatacept is scarce, so they should be considered only in cases refractory to rituximab. Rituximab is the biological agent of choice in severe extraglandular manifestations of pSS. Belimumab or abatacept may be useful in selected cases.
PMID: 30683506
URI: https://hdl.handle.net/20.500.12530/55686
Appears in Collections:Fundaciones e Institutos de Investigación > FIIB H. U. Infanta Sofía y H. U. Henares > Artículos

Files in This Item:
The file with the full text of this item is not available due to copyright restrictions or because there is no digital version. Authors can contact the head of the repository of their center to incorporate the corresponding file.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.