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Title: Cardiovascular risk factors associated with acute myocardial infarction and stroke in the MADIABETES cohort.
Issue Date: 27-Jul-2021
Citation: Sci Rep.2021;(11)1:15245
Abstract: We aimed to develop two models to estimate first AMI and stroke/TIA, respectively, in type 2 diabetes mellitus patients, by applying backward elimination to the following variables: age, sex, duration of diabetes, smoking, BMI, and use of antihyperglycemic drugs, statins, and aspirin. As time-varying covariates, we analyzed blood pressure, albuminuria, lipid profile, HbA1c, retinopathy, neuropathy, and atrial fibrillation (only in stroke/TIA model). Both models were stratified by antihypertensive drugs. We evaluated 2980 patients (52.8% women; 67.3 ± 11.2 years) with 24,159 person-years of follow-up. We recorded 114 cases of AMI and 185 cases of stroke/TIA. The factors that were independently associated with first AMI were age (≥ 75 years vs.  64 mmol/mol vs. 
PMID: 34315938
Rights: openAccess
Appears in Collections:Centros de Atención Primaria > Artículos

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