Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/56187
Title: Efficacy and tolerability of the hexanic extract of Serenoa repens compared to tamsulosin in moderate-severe LUTS-BPH patients.
Authors: 
Mesh: 
Issue Date: 29-Sep-2021
Citation: Sci Rep.2021;(11)1:19401
Abstract: In a subset analysis of data from a 6-month, multicenter, non-interventional study, we compared change in symptoms and quality of life (QoL), and treatment tolerability, in men with moderate to severe lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH) receiving tamsulosin (TAM, 0.4 mg/day) or the hexanic extract of Serenoa repens (HESr, 320 mg/day) as monotherapy. Symptoms and QoL were assessed using the IPSS and BII questionnaires, respectively. Patients in the treatment groups were matched using two statistical approaches (iterative and propensity score matching). Within the iterative matching approach, data was available from a total of 737 patients (353 TAM, 384 HESr). After 6 months, IPSS scores improved by a mean (SD) of 5.0 (4.3) points in the TAM group and 4.5 (4.7) points in the HESr group (p = 0.117, not significant). Improvements in QoL were equivalent in the two groups. TAM patients reported significantly more adverse effects than HESr patients (14.7% vs 2.1%; p 
PMID: 34588509
URI: https://hdl.handle.net/20.500.12530/56187
Rights: openAccess
Appears in Collections:Centros de Atención Primaria > Artículos

Files in This Item:
File SizeFormat 
PMC8481292.pdf1.17 MBAdobe PDFView/Open


This item is licensed under a Creative Commons License Creative Commons