Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/56559
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dc.contributor.authorGiráldez-García, Carolina
dc.contributor.authorCea-Soriano, Lucía
dc.contributor.authorAlbaladejo, Romana
dc.contributor.authorFranch-Nadal, Josep
dc.contributor.authorMata-Cases, Manel
dc.contributor.authorDíez-Espino, Javier
dc.contributor.authorArtola, Sara
dc.contributor.authorSerrano, Rosario
dc.contributor.authorRegidor, Enrique
dc.contributor.authorPREDAPS Study Group
dc.date.accessioned2022-12-19T11:35:24Z-
dc.date.available2022-12-19T11:35:24Z-
dc.date.issued2021-05-06
dc.identifier.citationSci Rep.2021;(11)1:9667
dc.identifier.urihttps://hdl.handle.net/20.500.12530/56559-
dc.description.abstractHealthy lifestyle interventions and drug therapies are proven to have a positive preventative influence on normal glucose regulation in prediabetes. However, little is known on the specific role that these factors play on reversion to normal glycemia according to type of prediabetes. We used data from the Observational prospective cohort study, The Cohort study in Primary Health Care on the Evolution of Patients with Prediabetes from 2012 to 2015. A total of 1184 individuals aged 30-74 years old were included and classified based on the ADA in three mutually exclusive groups using either fasting plasma glucose (FPG) levels (from 100 to 125 mg/dl, FPG group), HbA1c (5.7-6.4%, HbA1c group) or both impaired parameters. Information on lifestyle factors and biochemical parameters were collected at baseline. Reversion to normal glucose regulation was calculated at third year of follow-up. Relationship of lifestyle factor and type of prediabetes with reversion were estimated using odds ratios (ORs) with 95% confidence intervals (95% CIs) adjusting by different groups of confounders. Proportion of reversion rates were 31% for FPG group, 31% for HbA1c group and 7.9% for both altered parameters group, respectively. Optimal life style factors such as BMI 
dc.language.isoen
dc.rightsopenAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBlood Glucose
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshHealthy Lifestyle
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshPrediabetic State
dc.subject.meshProspective Studies
dc.subject.meshRisk Factors
dc.subject.meshSpain
dc.titleThe heterogeneity of reversion to normoglycemia according to prediabetes type is not explained by lifestyle factors.
dc.typeArtículo
dc.identifier.pubmedID33958606
dc.format.volume11
dc.format.page9667
dc.identifier.e-issn2045-2322
dc.identifier.journalScientific reports
dc.identifier.journalabbreviationSci Rep
dc.identifier.doi10.1038/s41598-021-87838-z
dc.format.number1
dc.identifier.pmcPMC8102601
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102601/pdf
Appears in Collections:Fundaciones e Institutos de Investigación > IIS H. U. Clínico San Carlos > Artículos
Centros de Atención Primaria > Artículos
Hospitales > H. U. Tajo > Artículos

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