Reliability and Validity of the 6-Minute Walk Test in Hypophosphatasia.

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Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12530/56776

Title:	Reliability and Validity of the 6-Minute Walk Test in Hypophosphatasia.
Authors:	Phillips, Dawn Tomazos, Ioannis C Moseley, Scott L'Italien, Gil Gomes da Silva, Hugo Lerma Lara, Sergio View more
Keywords:	AMBULATION BONE DISEASES METABOLIC MINIMAL CLINICALLY IMPORTANT DIFFERENCE QUALITY OF LIFE VALIDATION STUDIES View more
Issue Date:	1-Mar-2019
Citation:	JBMR Plus.2019;(3)6:e10131
Abstract:	This investigation evaluated the reliability and validity of the 6-Minute Walk Test (6MWT) in patients with pediatric hypophosphatasia (HPP). Children (aged 6 to 12 years; n = 11), adolescents (13 to 17 years; n = 4), and adults (18 to 65 years; n = 9) completed the 6MWT at screening and baseline in two clinical studies of asfotase alfa. Test-retest reliability of the 6MWT, evaluated with Pearson's correlation coefficients (r) for screening versus baseline, was high for children (r = 0.95; p
PMID:	31346563
URI:	https://hdl.handle.net/20.500.12530/56776
Rights:	openAccess
Appears in Collections:	Fundaciones e Institutos de Investigación > FIB H. Infantil U. Niño Jesús > Artículos

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