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Title: Argyrophilic grain disease presenting as behavioral frontotemporal dementia.
Issue Date: 2019
Citation: Clin Neuropathol.2019;(38)1:8-13
Abstract: Argyrophilic grain disease (AgD) is a frequent late-onset 4R tauopathy of old age characterized by the presence of profuse spindle-shaped argyrophilic grains (AGs). It is a neurodegenerative disorder that is clinically characterized by a slow progressive amnestic mild cognitive impairment similar to Alzheimer's disease. In rare instances, it is characterized as a behavioral-variant frontotemporal dementia (bv-FTD). In this study, we report a case with typical clinical and neuroimaging features of bv-FTD, who had autopsy findings consistent with a definitive diagnosis of AgD. We suggest that AgD might be included in the differential diagnosis of patients presenting with bv-FTD.
PMID: 30415651
ISSN: 0722-5091
Appears in Collections:Hospitales > H. U. Infanta Cristina > Artículos

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