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dc.contributor.authorSantos García, D
dc.contributor.authorde Deus Fonticoba, T
dc.contributor.authorSuárez Castro, E
dc.contributor.authorBorrué, C
dc.contributor.authorMata, M
dc.contributor.authorSolano Vila, B
dc.contributor.authorCots Foraster, A
dc.contributor.authorÁlvarez Sauco, M
dc.contributor.authorRodríguez Pérez, A B
dc.contributor.authorVela, L
dc.contributor.authorMacías, Y
dc.contributor.authorEscalante, S
dc.contributor.authorEsteve, P
dc.contributor.authorReverté Villarroya, S
dc.contributor.authorCubo, E
dc.contributor.authorCasas, E
dc.contributor.authorArnaiz, S
dc.contributor.authorCarrillo Padilla, F
dc.contributor.authorPueyo Morlans, M
dc.contributor.authorMir, P
dc.contributor.authorMartinez-Martin, P
dc.contributor.authorCoppadis Study Group
dc.identifier.citationParkinsonism Relat Disord.2019;(66):151-157
dc.description.abstractTo identify factors related to a poor health-related and global quality of life (QoL) in a cohort of non-demented Parkinson's disease (PD) patients and compare to a control group. The data correspond to the baseline evaluation of the COPPADIS-2015 Study, an observational, 5-year follow-up, multicenter, evaluation study. Three instruments were used to assess QoL: (1) the 39-item Parkinson's disease Questionnaire (PDQ-39), (2) a subjective rating of global QoL (PQ-10), and (3) the EUROHIS-QOL 8-item index (EUROHIS-QOL8). Multiple linear regression methods were used to evaluate the direct impact of different variables on these QoL measures. QoL was worse in PD patients (n = 692; 62.6 ± 8.9 years old, 60.3% males) than controls (n = 206; 61 ± 8.3 years old, 49.5% males): PDQ-39, 17.1 ± 13.5 vs 4.4 ± 6.3 (p  QoL is worse in PD patients than in controls. Mood, non-motor symptoms burden, and gait problems seem to be the most relevant factors affecting health-related and global perceived QoL in non-demented PD patients.
dc.subjectMotor fluctuations
dc.subjectNon-motor symptoms
dc.subjectParkinson's disease
dc.subjectQuality of life
dc.subject.meshAffective Symptoms
dc.subject.meshFollow-Up Studies
dc.subject.meshGait Disorders, Neurologic
dc.subject.meshMiddle Aged
dc.subject.meshParkinson Disease
dc.subject.meshQuality of Life
dc.subject.meshSeverity of Illness Index
dc.titleNon-motor symptoms burden, mood, and gait problems are the most significant factors contributing to a poor quality of life in non-demented Parkinson's disease patients: Results from the COPPADIS Study Cohort.
dc.identifier.journalParkinsonism & related disorders
dc.identifier.journalabbreviationParkinsonism Relat Disord
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
dc.pubmedtypeObservational Study
dc.pubmedtypeResearch Support, Non-U.S. Gov't
Appears in Collections:Hospitales > H. U. Infanta Sofía > Artículos

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